Mixed gases are used in many fields where a single gas cannot meet specific technical or safety requirements. In welding and metal fabrication, gas mixtures such as argon–CO₂ or argon–helium improve arc stability, weld quality, and penetration. In medical applications, breathing gas mixtures are used in anesthesia, respiratory therapy, and diving to ensure safe oxygen levels and reduce breathing resistance.

In industrial and scientific applications, mixed gases are widely used for calibration of gas detectors and analytical instruments, ensuring accurate measurements. They are also used in laboratories for research, controlled atmospheres, and chemical analysis. In addition, mixed gases play an important role in aerospace, electronics, and manufacturing processes, where precise gas compositions are required for purging, testing, and maintaining safe working environments.